Gut Microbiota Deficiency Reduces Neutrophil Activation and Is Protective after Ischemic Stroke.Tuz, A. A.; Ghosh, S.; Karsch, L.; Antler, M.; Lakovic, V.; Lohmann, S.; Lehmann, A. H.; Beer, A.; Nagel, D.; Jung, M.; Hörenbaum, N.; Kaygusuz, V.; Qefalia, A.; Alshaar, B.; Amookazemi, N.; Bolsega, S.; Basic, M.; Siveke, J. T.; Heiles, S.; Grüneboom, A.; Lueong, S.; Herz, J.; Sickmann, A.; Hagemann, N.; Hasenberg, A.; Hermann, D. M.; Gunzer, M.; Singh, V.
2025 J Neuroinflammation
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Risk beyond neutropenia: insights into neutrophil migration from newly diagnosed AML until late after allogeneic stem cell transplantationCibir, Z.; Beer, A.; Kraus, A.; Pillibeit, A.; Bludau, D.; Abdulla, H.; Neuendorff, N. R.; Sonneck, J.; Kowitz, L.; Riese, S.; Tuz, A. A.; Chen, J.; Cherneha, M.; Beelen, D. W.; Reinhardt, H. C.; Gunzer, M.; Turki, A. T.
2025 J Leukoc Biol
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Inhibition of Tumour Necrosis Factor Alpha by Etanercept Attenuates Shiga Toxin-Induced Brain PathologyChrist, R.; Siemes, D.; Zhao, S.; Widera, L.; Spangenberg, P.; Lill, J.; Thiebes, S.; Bottek, J.; Borgards, L.; Pinho, A. G.; Silva, N. A.; Monteiro, S.; Jorch, S. K.; Gunzer, M.; Siebels, B.; Voss, H.; Schlüter, H.; Shevchuk, O.; Chen, J.; Engel, D. R.
2025 J Neuroinflammation
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msiFlow: automated workflows for reproducible and scalable multimodal mass spectrometry imaging and microscopy data analysisSpangenberg, P.; Bessler, S.; Widera, L.; Bottek, J.; Richter, M.; Thiebes, S.; Siemes, D.; Krauß, S. D.; Migas, L. G.; Kasarla, S. S.; Phapale, P.; Kleesiek, J.; Führer, D.; Moeller, L. C.; Heuer, H.; Van de Plas, R.; Gunzer, M.; Soehnlein, O.; Soltwisch, J.; Shevchuk, O.; Dreisewerd, K.; Engel, D. R.
2025 Nat Commun
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Hypercholesterolemia triggers innate immune imbalance and transforms brain infarcts after ischemic strokeTuz, A. A.; Hoerenbaum, N.; Ulusoy, Ö.; Ahmadi, A.; Gerlach, A.; Beer, A.; Kraus, A.; Hasenberg, A.; Hagemann, N.; Hermann, D. M.; Gunzer, M.; Singh, V.
2025 Front. Immunol.
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Arterial Specification Precedes Microvascular Restitution in the Peri-Infarct Cortex That Is Driven by Small MicrovesselsHagemann, N.; Qi, Y.; Mohamud Yusuf, A.; Li, A.; Zhang, X.; Spangenberg, P.; Squire, A.; Doeppner, T. R.; Jin, F.; Zhao, S.; Chen, J.; Mosig, A.; Gunzer, M.; Hermann, D. M.
2024 J Cereb Blood Flow Metab
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Stroke and Myocardial Infarction Induce Neutrophil Extracellular Trap Release Disrupting Lymphoid Organ Structure and Immunoglobulin SecretionTuz, A. A.; Ghosh, S.; Karsch, L.; Ttoouli, D.; Sata, S. P.; Ulusoy, Ö.; Kraus, A.; Hoerenbaum, N.; Wolf, J.-N.; Lohmann, S.; Zwirnlein, F.; Kaygusuz, V.; Lakovic, V.; Tummes, H.-L.; Beer, A.; Gallert, M.; Thiebes, S.; Qefalia, A.; Cibir, Z.; Antler, M.; Korste, S.; Haj Yehia, E.; Michel, L.; Rassaf, T.; Kaltwasser, B.; Abdelrahman, H.; Mohamud Yusuf, A.; Wang, C.; Yin, D.; Haeusler, L.; Lueong, S.; Richter, M.; Engel, D. R.; Stenzel, M.; Soehnlein, O.; Frank, B.; Solo-Nomenjanahary, M.; Ho-Tin-Noé, B.; Siveke, J. T.; Totzeck, M.; Hoffmann, D.; Grüneboom, A.; Hagemann, N.; Hasenberg, A.; Desilles, J.-P.; Mazighi, M.; Sickmann, A.; Chen, J.; Hermann, D. M.; Gunzer, M.; Singh, V.
2024 Nat Cardiovasc Res
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ComplexEye: a multi-lens array microscope for high-throughput cell migration analysis |
Microvascular Network Remodeling in the Ischemic Mouse Brain Defined by Light Sheet MicroscopyHagemann, N.; Qi, Y.; Mohamud Yusuf, A.; Li, A.; Squire, A.; Tertel, T.; Giebel, B.; Ludewig, P.; Spangenberg, P.; Chen, J.; Mosig, A.; Gunzer, M.; Hermann, D. M.
2024 Arterioscler Thromb Vasc Biol
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Neural precursor cell delivery induces acute post-ischemic cerebroprotection, but fails to promote long-term stroke recovery in hyperlipidemic mice due to mechanisms that include pro-inflammatory responses associated with brain hemorrhagesYin, D.; Wang, C.; Qi, Y.; Wang, Y.-C.; Hagemann, N.; Mohamud Yusuf, A.; Dzyubenko, E.; Kaltwasser, B.; Tertel, T.; Giebel, B.; Gunzer, M.; Popa-Wagner, A.; Doeppner, T. R.; Hermann, D. M.
2023 J Neuroinflammation
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ComplexEye: a multi-lens array microscope for high-throughput embedded immune cell migration analysisCibir, Z.; Hassel, J.; Sonneck, J.; Kowitz, L.; Beer, A.; Kraus, A.; Hallekamp, G.; Rosenkranz, M.; Raffelberg, P.; Olfen, S.; Smilowski, K.; Burkard, R.; Helfrich, I.; Tuz, A. A.; Singh, V.; Ghosh, S.; Sickmann, A.; Klebl, A.-K.; Eickhoff, J. E.; Klebl, B.; Seidl, K.; Chen, J.; Grabmaier, A.; Viga, R.; Gunzer, M.
2023 Nat Rev Immunol
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Externalized Histones Fuel Pulmonary Fibrosis via a Platelet-Macrophage Circuit of TGFβ1 and IL-27Riehl, D. R.; Sharma, A.; Roewe, J.; Murke, F.; Ruppert, C.; Eming, S. A.; Bopp, T.; Kleinert, H.; Radsak, M. P.; Colucci, G.; Subramaniam, S.; Reinhardt, C.; Giebel, B.; Prinz, I.; Guenther, A.; Strand, D.; Gunzer, M.; Waisman, A.; Ward, P. A.; Ruf, W.; Schäfer, K.; Bosmann, M.
2023 Proceedings of the National Academy of Sciences
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Rapid and Fully Automated Blood Vasculature Analysis in 3D Light-Sheet Image Volumes of Different OrgansSpangenberg, P.; Hagemann, N.; Squire, A.; Förster, N.; Krauß, S. D.; Qi, Y.; Yusuf, A. M.; Wang, J.; Grüneboom, A.; Kowitz, L.; Korste, S.; Totzeck, M.; Cibir, Z.; Tuz, A. A.; Singh, V.; Siemes, D.; Struensee, L.; Engel, D. R.; Ludewig, P.; Nascentes Melo, L. M.; Helfrich, I.; Chen, J.; Gunzer, M.; Hermann, D. M.; Mosig, A.
2023 Cell Reports Methods
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A20 and the Noncanonical NF-κB Pathway Are Key Regulators of Neutrophil Recruitment during Fetal OntogenyRohwedder, I.; Wackerbarth, L. M.; Heinig, K.; Ballweg, A.; Altstätter, J.; Ripphahn, M.; Nussbaum, C.; Salvermoser, M.; Bierschenk, S.; Straub, T.; Gunzer, M.; Schmidt-Supprian, M.; Kolben, T.; Schulz, C.; Ma, A.; Walzog, B.; Heinig, M.; Sperandio, M.
2023 JCI Insight
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During Early Stages of Cancer, Neutrophils Initiate Anti-Tumor Immune Responses in Tumor-Draining Lymph NodesPylaeva, E.; Korschunow, G.; Spyra, I.; Bordbari, S.; Siakaeva, E.; Ozel, I.; Domnich, M.; Squire, A.; Hasenberg, A.; Thangavelu, K.; Hussain, T.; Goetz, M.; Lang, K. S.; Gunzer, M.; Hansen, W.; Buer, J.; Bankfalvi, A.; Lang, S.; Jablonska, J.
2022 Cell Reports
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Pathological neutrophil migration predicts adverse outcomes in hospitalized patients with liver cirrhosisLanger, M.-M.; Sichelschmidt, S.; Bauschen, A.; Bornemann, L.; Guckenbiehl, S.; Gunzer, M.; Lange, C. M.
2022 Liver International
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Ischemic stroke and concomitant gastrointestinal complications- a fatal combination for patient recoveryTuz, A. A.; Hasenberg, A.; Hermann, D. M.; Gunzer, M.; Singh, V.
2022 Frontiers in Immunology
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